Schematic of Mindboggle’s graph-based database of anatomical features. Top: different structures derived from brain images: surface patches fragmented by application of the Laplace-Beltrami operator, sulcus folds and subfolds, and structures within a subfold. Bottom: schematic graph diagrams representing the relationships among the nested structures. Bottom right: examples of features as properties of edges (relationships such as Part of, Connected to, Has label) and nodes (geometric, shape, and spectral measures).